Treatment Of Herpes Simplex Virus Type 1 Infection In Immunocompetent Patients
The clinical manifestations and treatment of primary and episodic recurrent hsv infections are discussed elsewhere. Herpes simplex virus 1 and 2 hsv 1 and hsv 2 also known by their taxonomical names human alphaherpesvirus 1 and human alphaherpesvirus 2 are two members of the human herpesviridae family a set of viruses that produce viral infections in the majority of humans.
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Both hsv 1 which produces most cold sores and hsv 2 which produces most genital herpes are common and contagious.
Treatment of herpes simplex virus type 1 infection in immunocompetent patients. Hsv 1 is responsible for. Genital and labial herpes simplex virus infections are frequently encountered by primary care physicians in the united states. Hsv 1 can also lead to clinical disease in a wide variety of other anatomic locations including the genitalia liver lung eye and central nervous system.
See epidemiology clinical manifestations and diagnosis of herpes simplex virus type 1 infection and treatment of herpes simplex virus type 1 infection in immunocompetent patients. In general the pathogenesis of hsv 1 infection follows a cycle of primary infection of epithelial cells latency primarily in neurons and reactivation. Its structure is composed of linear dsdna an icosahedral capsid that is 100 to 110 nm in diameter with a spikey envelope.
Herpes simplex virus type 1 hsv 1 may cause vesicular lesions of the lips and oral mucosa. The aim of the present report was to critically examine the published literature to evaluate the advantages and limitations of therapy of hsv 1 infection in both immunocompetent and immunocompromised. Hsv 1 infections are common in oral and perioral area.
Herpes simplex virus type 1 hsv 1 is a member of the alphaherpesviridae subfamily. Whereas the diagnosis of this condition is often straightforward choosing an appropriate drug eg acyclovir valacyclovir hydrochloride or famciclovir and dosing regimen. Herpes simplex virus type 1 hsv 1 gives rise to a variety of clinical disorders and is a major cause of morbidity and mortality worldwide.
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